课题基金 / 基金详情

Novel endonuclease-targeted approaches to nephroprotection

Novel endonuclease-targeted approaches to nephroprotection
新型核酸内切酶靶向肾保护方法
批准号：
7903377
负责人：
Alexei G Basnakian
金额：
$0.0万
依托单位：
CENTRAL ARKANSAS VETERANS HLTHCARE SYS
依托单位国家：
美国
项目类别：
财政年份：
2009
资助国家：
美国
项目状态：
已结题
起止时间：
2009-10-01 至 2013-09-30
来源：
https://reporter.nih.gov/project-details/7903377
关键词：
AcuteAcute Renal Failure with Renal Papillary NecrosisAffectAntioxidantsApoptosisApoptoticAutopsyBiological AssayBiologyCell DeathCell NucleusCellsCeramidesChemicalsCytoplasmDNADNA DamageDNA FragmentationDNA MethylationDataDeoxyribonuclease IDependovirusDevelopmentDiseaseDown-RegulationEnsureEnzyme Inhibitor DrugsEnzyme InhibitorsEnzymesEpigenetic ProcessEpithelialEpithelial CellsEpitheliumEventFundingFutureGeneral PopulationGlycerolGoalsGrant ReviewHealthHealthcareHeat shock proteinsHeat-Shock Proteins 70HeminHemodialysisHemolysisHourHumanIn Situ Nick-End LabelingIn VitroInjuryIonizing radiationKidneyKidney TransplantationKnockout MiceKnowledgeLeadLifeMeasurementMeasuresMediatingMedicalMethodsMilitary PersonnelMitochondriaMolecularMusMyoglobinNecrosisOrganOxidative StressPathologistPeptidesPharmaceutical PreparationsPoisonPopulationProductionPropertyRNA InterferenceReactive Oxygen SpeciesRegulationReportingResearchResistanceRhabdomyolysisScientistSkeletal MuscleTestingTherapeuticTimeTissuesToxic Environmental SubstancesToxic effectToxinTraumaTubular formationVeteransWalkersZincadeno-associated viral vectoraminothiolarmbasecell injurycell typecytotoxicdesigndisabilityendonucleaseendonuclease Genzyme activityexperienceimprovedin vitro Modelin vitro testingin vivoin vivo Modelinhibitor/antagonistinnovationkidney cellknockout genenovelnovel strategiesnovel therapeuticspathogenpre-clinicalpreclinical studypreventpublic health relevanceresearch studysmall hairpin RNAtooltraffickingvectorweapons

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BLRD Research Career Scientist Award Application
Cellular and Molecular Toxicology Core
  • 批准号：
    10025389
  • 项目类别：
  • 资助金额：
    $25.84万
  • 财政年份：
    2015
  • 负责人：
    Alexei G Basnakian
  • 依托单位：
    UNIV OF ARKANSAS FOR MED SCIS
Cellular and Molecular Toxicology Core
  • 批准号：
    10240506
  • 项目类别：
  • 资助金额：
    $25.84万
  • 财政年份：
    2015
  • 负责人：
    Alexei G Basnakian
  • 依托单位：
    UNIV OF ARKANSAS FOR MED SCIS
Cellular and Molecular Toxicology Core
  • 批准号：
    10487473
  • 项目类别：
  • 资助金额：
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  • 财政年份：
    2015
  • 负责人：
    Alexei G Basnakian
  • 依托单位：
    UNIV OF ARKANSAS FOR MED SCIS