Alzheimer Mouse Model for Intraneuronal Amyloid-Beta Oligomer Biology

用于神经元内淀粉样蛋白-β寡聚体生物学的阿尔茨海默病小鼠模型

• 批准号: 7907854
• 负责人: SAMUEL E. GANDY
• 金额: --
• 依托单位: JAMES J PETERS VA MEDICAL CENTER
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-10-01 至 2013-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7907854
• 关键词: Age; Alzheimer' s Disease; Amyloid; Amyloid beta-Protein; Appearance; Attention; Behavior assessment; Behavioral; Biochemical; Biology; Brain; Cerebral Amyloid Angiopathy; Dementia; Deposition; Development; Exons; Freedom; Functional disorder; Gender; Genes; Genetic; Hippocampus (Brain); Histopathology; Impaired cognition; Incidence; Learning; Life; Longevity; Mediator of activation protein; Memory; Modeling; Mus; Neurons; Pathology; Performance; Pharmaceutical Preparations; Population; Prevalence; Proteins; Senile Plaques; Severities; Sorting - Cell Movement; Structure; Synaptophysin; System; Testing; Time; Transgenic Mice; Transgenic Organisms; Traumatic Brain Injury; Variant; Veterans; World War II; age related; human very old age (85+); immunoreactivity; in vivo; intraneuronal beta amyloid; morphometry; morris water maze; mouse model; mutant; neuropathology; operation; overexpression; presenilin; prevent; promoter; public health relevance