Iron Acquisition by Mycobacterium tuberculosis Within Phagocytes

吞噬细胞内结核分枝杆菌对铁的获取

• 批准号: 7784541
• 负责人: BRADLEY E BRITIGAN
• 金额: --
• 依托单位: CINCINNATI VA MEDICAL CENTER RESEARCH
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-04-01 至 2013-09-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7784541
• 关键词: Acute; Anemia due to Chronic Disorder; Antibiotics; Antitubercular Agents; Bacteria; Bone Marrow; Cell membrane; Cells; Cellular biology; Chronic; Citrates; Clinical; Confocal Microscopy; Culture Media; Cytoplasm; Data; Defensins; Dendritic Cells; Development; Disease; Drug resistance in tuberculosis; Enzyme-Linked Immunosorbent Assay; FDA approved; Family; Francisella tularensis; Functional disorder; Gallium; Gene Mutation; Genetic; Growth; Health; Heme; Hepatocyte; Hereditary hemochromatosis; Homeostasis; Host Defense; Human; Hypercalcemia of Malignancy; Immunoblot Analysis; In Vitro; Individual; Infection; Interferons; Interleukin-6; Iron; Kinetics; Lactoferrin; Lead; Life; Link; Liver; Locales; Lung; Measures; Mediating; Metabolic Pathway; Metabolism; Methods; Microbe; Microbial Biofilms; Minority; Mission; Modeling; Movement; Multi-Drug Resistance; Mus; Mycobacterium tuberculosis; Myelogenous; Nature; Organism; Pathogenesis; Patients; Peptides; Phagocytes; Phagosomes; Pharmaceutical Preparations; Physiological; Platelet Factor 4; Play; Predisposition; Prevalence; Prevention strategy; Process; Production; Protein Export Pathway; Proteins; Pseudomonas aeruginosa; Pulmonary Tuberculosis; Research Support; Resistance; Reverse Transcriptase Polymerase Chain Reaction; Role; Route; Serum; Severity of illness; Siderophores; Site; Small Interfering RNA; Source; Spleen; Testing; Therapeutic Agents; Transferrin; Transition Elements; Tuberculosis; Veterans; Virulent; Work; base; cell type; cytokine; extracellular; heme oxygenase-1; hepcidin; high risk; in vivo; insight; macrophage; metal transporting protein 1; microbial; microbicide; novel; novel strategies; pathogen; public health relevance; response; trafficking; treatment strategy; tuberculosis drugs; tuberculosis treatment; uptake