Mechanisms of CDX2 regulation of the IGF axis

CDX2调节IGF轴的机制

• 批准号: 7789644
• 负责人: DUYEN DANG
• 金额: --
• 依托单位: VETERANS HEALTH ADMINISTRATION
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-04-01 至 2013-09-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7789644
• 关键词: Adult; Affect; Age; American; Apoptosis; CDX2 gene; CDX2 protein; Cancer Etiology; Carcinoma; Cell Proliferation; Cessation of life; Clinical; Colitis; Colon; Colon Adenocarcinoma; Colon Carcinoma; Colonic Adenoma; Colonic Neoplasms; Colorectal Adenoma; Colorectal Cancer; Colorectal Neoplasms; Data; Development; Disease; Drosophila genus; Epithelial Cells; Goals; Growth; Homeobox; Homeobox Genes; Immunoprecipitation; In Vitro; Individual; Insulin-Like Growth Factor Binding Protein 3; Intestinal Metaplasia; Intestines; Investigation; Knockout Mice; Large Intestine Carcinoma; Lead; Link; Maintenance; Malignant Neoplasms; Mucous Membrane; Mus; Mutation; Oncogenic; Patients; Play; Population; Premalignant; Property; Protein p53; Regulation; Role; Series; Signal Pathway; Signal Transduction; Solid Neoplasm; Somatomedins; Stomach; Testing; Tumor Suppressor Genes; Tumor Suppressor Proteins; United States; Veterans; adenoma; cancer prevention; cancer therapy; cell growth; colon cancer cell line; high risk; in vivo; inhibitor/antagonist; insight; intestinal epithelium; leukemia; metaplastic cell transformation; mutant; novel; promoter; protein protein interaction; public health relevance; response; transcription factor; tumor; tumor growth; tumor initiation; tumor progression; tumorigenesis