CCTN - 长效可逆避孕药的临床评估-猫眼课题宝

CCTN - 长效可逆避孕药的临床评估

批准号：

9150718

负责人：

DAVID TUROK

金额：

$32.52万

依托单位：

UNIVERSITY OF UTAH

依托单位国家：

美国

项目类别：

财政年份：

2015

资助国家：

美国

项目状态：

已结题

起止时间：

2015-09-25 至 2018-09-24

来源：

https://reporter.nih.gov/project-details/9150718

关键词：

Attitude CCL20 gene Chlamydia Clinical Clinical Practice Guideline Contraceptive Agents Contraceptive History Contraceptive methods Contractor Contracts Copper Data Data Analyses Development Devices Dose Effectiveness Eligibility Determination Enrollment Ethinyl Estradiol Frequencies Future Gonorrhea Good Clinical Practice Guidelines Health Hemorrhage Hormonal Hormones Implant Incidence Informed Consent Instruction International Medical Methods Monitor Muscle Cramp National Institute of Child Health and Human Development Obesity Pain Pap smear Pattern Pharmaceutical Preparations Phase Pregnancy Pregnancy Tests Pregnant Women Preparation Procedures Property Protocols documentation Randomized Recording of previous events Records Recruitment Activity Regulation Reproductive History Risk Sampling Specific qualifier value Ultrasonography Urine Vaginal Ring Visit Woman Writing arm demographics factor V Leiden follow-up meetings protocol development research clinical testing screening standard of care symposium trial design xenoestrogen

中文摘要

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英文摘要

LARC methods include IUDs, implants, or long acting vaginal rings. LARC methods are more effective than daily, weekly or monthly products because they are less prone to user error. IUDs and implants have an effectiveness rate that is in the top tier for typical use (>99% effective). Development of new LARC methods is a high priority for the CDDB. LARC methods, copper-containing IUDs are the only highly effective reversible methods that do not involve administration of hormones and do not cause irregular or unscheduled bleeding pattern in women. These properties make a copper IUD and ideal method for women who do not wish to take or cannot take hormonal contraceptive methods. Products containing the synthetic estrogen and ethinyl estradiol have been associated with a dose-dependent increase in BTE. Copper IUDs do not increase risk of VTE, such as obese women, pregnant women and women with Leiden Factor V. Preliminary data from some studies indicate that newer copper IUDs may be associated with a lower incidence of heavy bleeding and/or cramping and some devices may have less pain with insertion.

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