TAS::75 0849::TAS THE GOAL OF THIS PROJECT IS TO DEVELOP STC TRASTUZUMAB, A GEN
TAS::75 0849::TAS THE GOAL OF THIS PROJECT IS TO DEVELOP STC TRASTUZUMAB, A GEN
批准号:
8164745
负责人:
MAGDALENA LESZCZYNIECKA
金额:
$29.99万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
2010
资助国家:
美国
项目状态:
已结题
起止时间:
2010-09-30 至 2011-06-30
关键词:
AddressBiochemicalChinese Hamster Ovary CellDevelopmentERBB2 geneEngineeringGeneric DrugsGoalsGovernmentHealthcareMonoclonal AntibodiesPatientsPharmaceutical PreparationsPhasePopulationPositioning AttributePost Translational Modification AnalysisProcessProteinsRecombinant ProteinsRoche brand of trastuzumabTrastuzumabcancer therapycostdrug developmentmalignant breast neoplasmoverexpressionprogramsreceptor binding
中文摘要
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英文摘要
The goal of this project is to develop STC trastuzumab, a generic version of Herceptin. Trastuzumab is a monoclonal antibody made against the HER2 protein that is overexpressed in 20-25% of patients with breast cancer. Because of very high cost associated with prescribing Herceptin, a generic version of this drug would make cancer treatment more affordable to a wider segment of the population and lower the cost burden on government-sponsored healthcare programs.
STC Biologics Inc. is uniquely positioned to address the technical challenge of reverse engineering trastuzumab as its drug development platform offers rapid and efficient analysis of post-translational modification of recombinant proteins.
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OTHER FUNCTIONS SBIR PHASE II TOPIC 275, "DEVELOPMENT OF GENERIC TRASTUZUMAB FOR
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批准号:8555067
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项目类别:
-
资助金额:$249.95万
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财政年份:2012
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负责人:MAGDALENA LESZCZYNIECKA
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依托单位:
海外基金