Center for Evaluation and Coordination of Training and Research in TRS

修改后的项目摘要/摘要部分 描述(由申请人提供)：在卫生实施科学的工作台到床边范式的模式中，烟草监管科学(TRS)面临着类似的挑战，即首先将当前的基础工作转化为正式的监管科学学科，最终(但很快)转化为最终导致减少与烟草相关的疾病和死亡的政策和监管实施。为了应对这一挑战，国家卫生研究院和食品和药物管理局需要一种机制来组织、监测、评估、反应和计划当前和未来的研究，既作为单独的项目，也作为一个协调、有目的的组合，遵循研究的发展道路，导致以科学为基础的烟草监管行动。经济、社会和文化权利委员会将是这一进程的核心。Westat很高兴与美国遗产基金会(Schroeder-Legacy)的施罗德烟草研究和政策研究所(Schroeder-Legacy)合作创建CECTR，其基本前提是，完成这一使命需要将TRS这一新兴领域的深厚科学技术专长和知识与管理大型协调中心和其他复杂支持项目的出色运营能力相结合。我们的方法由公共卫生硕士Jeanne Rosenthal(Westat)和博士David Abrams(Schroeder-Legacy)领导，配备了一批资深烟草科学家和经验丰富的评估人员，培训开发人员、方法学家、流行病学家、分析师和统计学家，在高度支持和高效的基础设施中提供科学领导和研究技术专长。WESTAT团队将致力于实现以下具体目标：(1)通过促进协作和交流，加速知识共享和创新；(2)为政策相关研究及时提供技术研究报告的概念模型、共同措施和其他工具；(3)通过协调CTP资助的科学家的跨学科培训，促进数据共享、分析和综合，提高研究界进行更迅速和更有效的技术研究的能力；以及(4)提高技术研究报告的质量和创新能力，并通过严格的评估过程，扩大研究能力，以产生为政策和实践提供信息的结果。

Modified Project Summary/Abstract Section DESCRIPTION (provided by applicant): In the mold of the bench-to-bedside paradigm for health implementation science, tobacco regulatory science (TRS) faces a similar challenge of translating the current foundational work first into a formal regulatory science discipline and eventually (but quickly) to policy and regulatory implementation that leads ultimately to the reduction of tobacco-related disease and death. To address this challenge, the National Institutes of Health and the Food and Drug Administration need a mechanism to organize, monitor, assess, react to, and plan current and future research, both as individual projects and as a harmonized, purposive portfolio that follows a developing path for the research, leading to science-based tobacco regulatory actions. The CECTR will be central to this process. Westat is pleased to join with the Schroeder Institute for Tobacco Research and Policy Studies of the American Legacy Foundation (Schroeder-Legacy) to create a CECTR based on the fundamental premise that fulfilling this mission requires an integration of deep scientific and technical expertise and knowledge in the nascent field of TRS with outstanding operational capabilities in managing large coordinating centers and other complex support projects. Led by co-PD/PIs Jeanne Rosenthal, MPH (Westat), and David Abrams, PhD (Schroeder-Legacy), and staffed by a cadre of senior tobacco scientists and highly experienced evaluators, training developers, methodologists, epidemiologists, analysts, and statisticians, our approach provides scientific leadership and research technical expertise within a highly supportive and efficient infrastructure. The Westat team will focus on achieving the following specific aims: (1) accelerate knowledge sharing and innovation by facilitating collaboration and communication; (2) increase the timely availability of TRS conceptual models, common measures and other tools for policy relevant research; (3) enhance the capacity of the research community to conduct more rapid and impactful TRS by coordinating cross-disciplinary training of CTP-funded scientists and facilitating data sharing, analysis, and synthesis; and (4) enhance the quality and innovativeness of TRS and expand the research capacity to produce results that inform policy and practice through a rigorous evaluation process.