Pilot and Feasibility Program

试点和可行性计划摘要 加州大学旧金山分校DRC的试点和可行性计划旨在为建立强有力的糖尿病研究做出贡献 通过实现以下目标实现加州大学旧金山分校的社区： ·确定、吸引和支持新的研究人员和初级教员建立糖尿病研究项目。 ·促进DRC/加州大学旧金山分校教职员工之间的新的创新合作。 ·使现有教员能够将技能和研究进展转移到糖尿病研究领域。 ·鼓励在基础和临床糖尿病研究中进行高度创新的早期研究。 ·提供种子资金，可用于增加新兴研究领域的外部赠款资金 在当前的资金周期内，DRC P&F计划通过 在6个申请中的63个申请中，总共为23个项目提供了980,000美元的资金。一个 另外3项提案(70,000美元)由加州大学旧金山分校糖尿病中心基金资助。DRC计划放置了一个 优先为打算建立与以下方面相关的研究项目的年轻教员提供支持 成功的申请者中有16人是新的/早期的研究人员。首席调查员 在资助的项目中，有8个是糖尿病研究的新成员，其余两个是已确定的糖尿病 研究人员提出了新的和特别创新的翻译研究方向。P&F计划 致力于促进所有希望在基础或临床糖尿病方面采取新举措的加州大学旧金山分校教职员工 研究。成功的研究计划在18个不同的部门进行或组织 研究单位和3个校区。 迄今为止，由种子资金发起的项目已出版了30份出版物，并成功地 竞相争取6,560,351美元的外部赠款资金，其中2,780,351美元流向早期调查人员。这 突出的回报反映了收到的申请的极高质量。作为这笔资金的结果 成功，以及P&F计划指导计划，除2名P&F奖获得者外，所有人仍患有糖尿病 其中8人现在是刚果民主共和国的常任理事国。在扩大和丰富 USCF糖尿病研究社区向加州大学旧金山分校糖尿病中心私人捐赠200万美元 扩大P&F计划。 我们的目标是在下一个周期取得这一成功的基础上再接再厉。我们的RFA将覆盖加州大学旧金山分校更广泛的细分市场 通过参加最近建立的全校范围内助学金支助系统。增加的平均数 资助金规模将吸引更多的优质申请，并允许资助商在 提出创新项目。最后，我们有令人兴奋的计划来改进我们的指导和反馈 确保我们的P&F赠款接受者充分利用当地专业知识的机制。

Summary Pilot & Feasibility Program The UCSF DRC's Pilot & Feasibility Program aims to contribute to the building of a robust diabetes research community at UCSF by fulfilling the following goals: • Identify, attract and support new investigators and junior faculty establishing research programs in diabetes. • Foster new and innovative collaborations amongst DRC/UCSF faculty. • Enable established faculty to transfer skills and research developments to the arena of diabetes research. • Encourage highly innovative early stage investigation in basic and clinical diabetes research. • Provide seed funding that can be leveraged to increase external grant funding in emerging areas of research During the current funding cycle, the DRC P&F Program supporting diabetes research at UCSF with a total of $980,000 in funding for 23 projects out of 63 applications over six Requests for Applications. An additional 3 proposals ($70,000) were funded with UCSF Diabetes Center funds. The DRC Program placed a high priority on providing support for young faculty intending to establish research programs relevant to diabetes, and 16 of the successful applicants were New/Early Stage Investigators. The Principle Investigators on 8 of the funded project were new to diabetes research, and the remaining two were established diabetes investigators proposing new and exceptionally innovative translational research directions. The P&F program was dedicated to facilitating all UCSF Faculty wishing to pursue new initiatives in basic or clinical diabetes research. The successful research programs were conducted in 18 different departments or Organized Research Units and 3 campuses. Projects that were initiated with seed funding have, to date, resulted in 30 publications and successfully competed for $6,560,351 in external grant funding, of which $2,780,351 went to early stage investigators. This outstanding return reflects the extremely high quality of the applications received. As a result of this funding success, and the P&F Program mentoring program, all but 2 of the P&F awardees remain in diabetes research, and 8 are now permanent members of the DRC. This success in expanding and enriching the diabetes research community at USCF lead to a 2 million dollar private donation to the UCSF Diabetes Center to expand the P&F program. Our goal is to build on this success in the coming cycle. Our RFAs will reach a broader segment of UCSF by participating in a recently set-up campus-wide intramural grants support system. The increased average grant size will capture an even larger number of high quality applications and permit grantees greater leeway in proposing innovative projects. Finally, we have exciting plans to improve our mentoring and feedback mechanisms that ensure our P&F grant recipients take full advantage of the local expertise.