Imaging Core

组织和成像核心将提供技术专长、培训和 用于组织处理和生物样本分析的最先进的仪器，包括 共聚焦显微镜和体视学。在上一份意见书中，我们没有组织学主任 和成像核心，转而提议招聘一名能够领导这一核心的高级科学家。我们有 在招聘工作中取得了成功，增加了杰弗里·博夫博士，他是一名疼痛研究人员，拥有 主要研究炎症如何影响初级传入伤害性神经元。博夫博士有 在神经和肌肉骨骼的组织学、图像采集、组织形态学方面有丰富的经验 结构和免疫荧光形态计量学。他用组织学的方法出版了许多手稿 和免疫组织学方法，以及使用电子显微镜。博夫博士还发现了 使用体视学和非体视学方法的免疫定量方法。此外，我们还有 招募了Cobre项目负责人威利斯博士，他在共焦和电子显微镜方面拥有专业知识，将为 作为联合主任，组织和成像核心主任将就最佳方法向调查人员提供建议 解决他们的问题，提供方法和工具方面的培训，并监督核心 经理/技术人员。

The Histology and Imaging Core will provide technical expertise, training, and state-of-the-art instrumentation for the processing of tissue and the analysis of biological samples, including confocal microscopy and stereology. In the previous submission, we did not have a Director for the Histology and Imaging Core and instead proposed to recruit a senior level scientist who could lead this Core. We have been successful in this recruitment effort with the addition of Dr Geoffrey Bove, a pain researcher with a primary focus on examining how inflammation affects primary afferent nociceptive neurons. Dr Bove has extensive experience in histology, image acquisition, histomorphology of neural and musculoskeletal structures, and immunofluorescent morphometry. He has published numerous manuscripts using histological and immunohistological methods, as well as using electron microscopy. Dr Bove has also developed immunoquantification methods using stereological and non-stereologicat approaches. In addition, we have recruited Dr Willis, a COBRE Project Leader with expertise in confocal and electron microscopy who will serve as co-Director The Histology and Imaging Core Directors will advise investigators on the best approach to address their questions, provide training in methodology and instrumentation, and to supervise the Core manager/technician.