Development of a Behavioral Economics Guided Just-In-Time Adaptive Intervention to Reduce Heavy Drinking and Loss-of-Control Eating in Female Young Adult Survivors of Sexual or Dating Violence

项目总结/摘要 建议的指导研究科学家发展奖的长期目标是推出博士。 Jacques-Tiura作为一名独立的社会健康行为变化研究人员， 关于年轻女性的成瘾行为这一目标将通过为期5年的平行培训来实现， 研究计划。培训目标包括：（1）T1翻译的理论和实践 行为经济学理论及其在成瘾研究中的应用 行为，（3）移动的健康提供（mHealth）干预措施的开发和完善，以及（4） 开发、完善和使用分析数据的统计方法，为适应性干预提供信息， 及时适应性干预（JITAIs）。培训目标将通过全面的培训来实现 计划包括（1）与导师Sylvie Naar博士、Mark Greenwald博士、Steven Ondersma和Inbal Nahum-Shani，（2）讲习班和暑期学院，（3）会议，（4）研讨会， (5)负责任地进行研究的课程。通过培训计划获得的技能将投入到 通过三个阶段的补充研究计划采取行动。第一阶段将在第一年和第二年完成， 涉及干预前发展的基本行为科学。为了实现目标1，我们将在网上收集 调查数据来自300名18-25岁的年轻女性，以检查与以下方面相关的常见行为经济因素： 性暴力和/或约会暴力幸存者的间歇性酗酒（HED）和饮食失控（LOC） （SVDV），如酒精和食品的相对强化价值，酒精和食品的延迟折扣，成本和 酒精和暴食的后果，以及非酒精和食物相关活动的强化。 结果将指导干预和开发以及第2阶段（T1翻译）的beta测试。第二阶段， 在第2-3年完成，涉及开发和beta测试12周的在线行为经济指导 JITAI减少12名SVDV幸存者的HED和进食行为，以解决目标2。第三阶段， 在第4年和第5年完成，重点是概念验证，涉及可行性和初步疗效 测试第二阶段开发的干预措施。目标3a涉及参与者的可行性和完善 方法和干预内容，目的3b涉及通过进行内部干预来测试发明功效。 对36名SVDV幸存者进行了多基线初步研究。拟议的研究将为以下方面提供试点数据： 博士Jacques-Tiura向NIAAA提交的第一份R 01提案，将于第5年提交。导师Naar博士、Greenwald博士、 Ondersma和Nahum-Shani将分享他们在以下方面的专业知识：（1）健康干预的T1翻译，（2） 行为经济学，（3）移动健康，（4）JITAI研究设计和统计分析。韦恩州立大学 大学提供了合适的资源和富有成效的环境，适合在成瘾者中发展职业生涯。 行为。该提案符合NIH研究职业发展计划的总体目标， 确保培训多样化的科学家，以满足美国的行为和生物医学需求。

PROJECT SUMMARY/ABSTRACT The long-term objective of the proposed Mentored Research Scientist Development Award is to launch Dr. Jacques-Tiura’s program of research as an independent social health behavioral change researcher focusing on young women’s addictive behaviors. This goal will be achieved through a 5-year parallel training and research plan. Training objectives involve building expertise in (1) the theory and practice of T1 translation intervention development and adaption, (2) behavioral economic theory and its application to addictive behaviors, (3) the development and refinement of mobile health-delivered (mHealth) interventions, and (4) the development, refinement, and use of statistical methods of analyzing data to inform adaptive interventions and just-in-time adaptive interventions (JITAIs). Training objectives will be met through a comprehensive training plan involving (1) ongoing one-on-one meetings with mentors Drs. Sylvie Naar, Mark Greenwald, Steven Ondersma, and Inbal Nahum-Shani, (2) workshops and summer institutes, (3) conferences, (4) seminars, and (5) coursework for the responsible conduct of research. Skills gained through the training plan will be put into action through the complementary three-phase research plan. Phase 1, to be completed in Years 1 and 2, involves basic behavioral science of pre-intervention development. To address Aim 1, we will collect online survey data from 300 young women age 18-25 to examine common behavioral economic factors related to heavy episodic drinking (HED) and loss-of-control (LOC) eating among sexual and/or dating violence survivors (SVDV), such as relative reinforcing value of alcohol and food, delay discounting of alcohol and food, costs and consequences of alcohol and LOC eating, and reinforcement from non-alcohol and food-related activities. Results will guide intervention and development and beta testing in Phase 2 (T1 translation). Phase 2, to be completed in Years 2-3, involves developing and beta testing the 12-week online behavioral economic-guided JITAI to reduce HED and LOC eating behaviors with 12 SVDV survivors, to address Aim 2. Phase 3, to be completed in Years 4 and 5, focuses on proof of concept and involves feasibility and preliminary efficacy testing of the intervention developing in Phase 2. Aim 3a concerns feasibility and refinement of participant methods and intervention content, and Aim 3b concerns testing invention efficacy by conducting a within- subjects multiple baseline pilot study with 36 SVDV survivors. The proposed studies will provide pilot data for Dr. Jacques-Tiura’s first R01 proposal to NIAAA, to be submitted in Year 5. Mentors Drs. Naar, Greenwald, Ondersma, and Nahum-Shani will share their expertise in (1) T1 translation of health intervention, (2) behavioral economics, (3) mHealth, and (4) JITAI research design and statistical analysis. Wayne State University offers suitable resources and a fruitful environment ripe for growing a career in the addictive behaviors. This proposal is aligned with the NIH Research Career Development program’s overall goal of ensuring the training of a diverse pool of scientists to address the USA’s behavioral and biomedical needs.