Data Management and Statistical Core

数据管理和统计核心摘要 耶鲁ADRC的数据管理和统计核心（DSMC）将提供数据管理和 提供统计支助，以满足业务需要和开展研究。耶鲁DMSC将由石楠Allore领导， 博士和Peter Charpentier，M.P.H.他们是生物统计学和数据管理的主管， 信息学核心，分别是耶鲁大学老龄化计划（POA）和克劳德D。胡椒老 耶鲁大学美国独立中心拟议的统计和数据管理方法 耶鲁DMSC是基于实践和系统开发和实施的POA和耶鲁的临床和 转化科学研究所-耶鲁大学临床研究中心（YCCI）-赞助了一个特别的 实施Oncore临床试验管理系统。耶鲁DMSC将利用计算机 以及POA和YCCI提供的资源基础设施。DSMC将开发适当的数据管理 用于受试者跟踪、累积和其他研究执行报告以及安全存储的系统和程序 关于EPHI这包括创建和管理所有临床数据的病例报告表（CRF），以及 作为基础神经科学实验室和一些临床研究项目的电子表格， 适用于UDS数据管理程序。在整个过程中，安全、符合HIPAA的数据 将采取管理措施。DMSC将与其他核心互动，以管理数据并提供 统计咨询以及教育和推广方案评价。此外，ADRC将提供 研究和试点项目的统计和分析文件将在一个去识别的SAS数据集市上创建。 DSMC的这些活动将共同确保整个过程中强大的数据管理和统计分析 耶鲁ADRC

SUMMARY OF DATA MANAGEMENT AND STATISTICS CORE The Data Management and Statistics Core (DSMC) of the Yale ADRC will provide data management and statistical support to meet the operational needs and research. The Yale DMSC will be led by Heather Allore, Ph.D. and Peter Charpentier, M.P.H. who are the directors of the Biostatics and the Data Management and Informatics Cores, respectively, of the Yale Program on Aging (POA) and of the Claude D. Pepper Older Americans Independence Center at Yale. The statistical and data management methodologies proposed for Yale DMSC are based on practices and systems developed and implemented at POA and Yale's Clinical and Translational Science Institute- the Yale Center for Clinical Investigations (YCCI) - that sponsors a special implementation of the Oncore Clinical Trial Management System. The Yale DMSC will leverage the computing and resource infrastructure provided by POA and YCCI. The DSMC will develop appropriate data management systems and procedures for subject tracking, accrual and other conduct-of-study reports, and secure storage of ePHI. This includes the creation and management of case report forms (CRFs) for all clinical data, as well as electronic spreadsheets for basic neuroscience laboratories and some clinical research projects, and a suitable procedure for UDS data management. Throughout these procedures secure, HIPAA-compliant data management practices will be employed. The DMSC will interact with other Cores to manage data and provide statistical consultation and educational and outreach program evaluation. Furthermore, the ADRC will provide research and pilot projects statistical and analysis files will be created on a de-identified SAS data mart . Together these activities of the DSMC will ensure robust data management and statistical analysis throughout the Yale ADRC.