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Bioinformatics Core

生物信息学核心

基本信息

批准号：
9119080
负责人：
MARY E DAVIS
金额：
$ 28.42万
依托单位：
MARSHALL UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
资助国家：
美国
起止时间：
至
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/9119080
关键词：
Admission activity Algorithms Applications Grants Area Aryl Hydrocarbon Receptor Award Back Behavior Binding Proteins Bioconductor Bioinformatics Biological Process Biomedical Research Blood - brain barrier anatomy Breast Cancer Cell Breeding CHD1 gene Canis familiaris Cardiovascular Diseases Carrier Proteins Categories Cellular biology ChIP-seq Charge Classification Collaborations Communicable Diseases Computational Science Computer Simulation Computers Conflict (Psychology)DNA Data Data Analyses Data Set Databases Detection Disease Doctor of Philosophy Eating Educational process of instructing Educational workshop Elements Emergency response Engineering Environment Exercise Experimental Designs Flavoring Funding GCG gene Gene Expression Gene Expression Regulation Generations Genes Genetic Genetic Programming Genome Genomic DNA Genomics Goals Homology Modeling Housing Human Human Microbiome Individual Information Technology Inherited Institutes Instruction Internet Internships Ivermectin Journals Learning Link Literature Malignant Neoplasms Marshal Mass Spectrum Analysis Mathematics Measures Methods Michigan Microarray Analysis Modeling Molecular Genetics Multi-Drug Resistance Mus Mutagenesis Mutation Online Mendelian Inheritance In Man Online Systems Ontology Organism Outcome Paper Participant Pathway Analysis Pathway interactions Patients Phase Pilot Projects Point Mutation Population Research Post-Translational Protein Processing Problem Sets Property Protein Databases Protein Family Proteins Proteome Proteomics Publications Quality Control RNA Research Research Personnel Research Project Grants Research Proposals Resources Scanning Science Scientist Sequence Analysis Services Sjogren&apos s Syndrome Software Tools Structure Students System Techniques Technology Time Training Travel Universities Virginia West Virginia Work abstracting base career certificate program college computer science computerized data processing computerized tools cost cyber infrastructure database structure design differential expression exome sequencing experience experimental analysis falls gene product genome sequencing graduate student helicase instructor interest knowledge base lectures markov model mathematical model medical schools meetings member microbiome multidisciplinary neurotoxicity next generation sequencing pathogen pathway tools programs protein structure research study statistics student training summer program symposium three dimensional structure tool transcriptome sequencing tumor growth undergraduate student university student vector web page whole genome

项目摘要

The Bioinformatics Core (BC) works with the WV-INBRE Genomics Core (GC) at Marshall University (MU) and West Virginia University (WVU) GC to deliver integrated analysis of Next Generation Sequencing (NGS) and microarray data sets. NGS and microarray data analysis are and will be provided to network investigators as a full service from planning and experimental design, through DNA/RNA Quality Control (QC), wet lab experimentation with Quality Analysis (QA), data analysis and interpretation, to delivery of results, and discussion of their significance and additional methods of analysis. Under our service model, investigators must meet with BC and GC staff to discuss experimental design, methods of analysis, expected outcomes and costs prior to the initiation of any experimentation (full description of service plan is provided under section 11(3)). A separate description of the GC as an optional Core is provided as part of this application. Members of the BC and the GC work together on most of these services.

生物信息学核心（BC）与马歇尔大学（MU）和西弗吉尼亚大学（WVU） GC的WV-INBRE基因组学核心（GC）合作，提供下一代测序（NGS）和微阵列数据集的集成分析。NGS和微阵列数据分析将为网络研究人员提供全面的服务，从规划和实验设计，到DNA/RNA质量控制（QC），湿实验室实验与质量分析（QA），数据分析和解释，到交付结果，讨论其意义和其他分析方法。在我们的服务模式下，研究人员必须在任何实验开始之前与BC和GC的工作人员会面，讨论实验设计、分析方法、预期结果和成本（服务计划的完整描述见第11(3)条）。作为此应用程序的一部分，提供了作为可选核心的GC的单独描述。BC和GC的成员在大多数这些服务上共同工作。