Laboratory Animal Resource Improvements- Utah State University

实验动物资源改善-犹他州立大学

• 批准号: 9119554
• 负责人: Aaron L. Olsen
• 金额: $ 21.34万
• 依托单位: UTAH STATE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2016
• 资助国家: 美国
• 起止时间: 2016-03-21 至 2018-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9119554
• 关键词: Animal Experimentation; Animals; Antiviral Therapy; Decontamination; Ensure; Failure; Funding; Future; Laboratories; Laboratory Animals; Research; Research Personnel; Therapeutic Studies; United States National Institutes of Health; Universities; Utah; Virus Diseases; animal care; animal resource; improved; operation; square foot

 DESCRIPTION (provided by applicant): A 3,847 square foot animal biosafety-level 3 laboratory at Utah State University serves NIH funded investigators involved in viral disease and antiviral therapy research. The laboratory has been hampered and threatened with closure due to repeated failure of the sole pass-through autoclave supporting the laboratory. To better serve the needs of the researchers and minimize the impact of autoclave failure on current and future viral disease studies, we propose to install an additional pass-through autoclave. This second autoclave will increase decontamination capacity and, more importantly, provide redundancy to ensure continuous laboratory operation. This in turn will improve animal care by ensuring that research animals will not need to be euthanized unnecessarily, and by advancing research aimed at developing treatment for viral infections.

 描述（由申请人提供）：犹他州州立大学的一个3，847平方英尺的动物生物安全3级实验室为NIH资助的参与病毒性疾病和抗病毒治疗研究的研究人员提供服务。由于支持该实验室的唯一直通式高压灭菌器一再发生故障，该实验室受到阻碍并面临关闭的威胁。为了更好地满足研究人员的需求，并最大限度地减少高压灭菌器故障对当前和未来病毒性疾病研究的影响，我们建议安装额外的直通高压灭菌器。这第二个高压灭菌器将增加净化能力，更重要的是，提供冗余，以确保连续的实验室操作。这反过来又将通过确保研究动物不需要被不必要地安乐死，并通过推进旨在开发病毒感染治疗方法的研究来改善动物护理。