IGF::OT::IGF SIMIAN VACCINE EVALUATION UNITS
IGF::OT::IGF SIMIAN VACCINE EVALUATION UNITS
批准号:
9364043
负责人:
HANNE ELYARD
金额:
$15.74万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
2016
资助国家:
美国
项目状态:
已结题
起止时间:
2016-05-01 至 2017-07-31
关键词:
AIDS VaccinesAIDS vaccine developmentAdvanced DevelopmentAwardClinicalComplementContractsDevelopmentEvaluation StudiesFundingGrantHIV vaccineImmuneIntegraseInvestigator-Initiated ResearchLentivirus VectorLocal MicrobicidesModalityNational Institute of Allergy and Infectious DiseasePreventionPrevention strategyResearch PersonnelResearch Project GrantsResourcesVaccine DesignVaccine ResearchVaccinesbaseimmunogenicitynonhuman primatepre-clinicalpreclinical evaluationpreclinical studyprogramsvaccine candidatevaccine evaluation
中文摘要
艾滋病毒疫苗和其他预防战略的发展依赖于在临床前研究中使用非人类灵长类动物,以促进有效艾滋病疫苗候选的开发,并促进有效局部杀微生物剂和其他预防方式或基于免疫的疗法的开发。NIAID猿猴疫苗评估单位(SVEU)的合同将提供主要支持艾滋病疫苗临床前评估的非人类灵长类资源。SVEU进行研究,以支持由广泛的调查人员开发的疫苗。这些研究是对NIAID支持的基础疫苗研究和疫苗评估研究的补充,这些研究由R01(研究人员发起的研究)拨款、HIVRAD(艾滋病毒疫苗研究和设计计划)拨款、IPCAVD(临床前-临床综合艾滋病疫苗开发)拨款和NHP联盟奖项资助。SVEU还对公司或其他研究人员提供的候选疫苗进行研究。
英文摘要
The development of HIV vaccines and other prevention strategies relies on the use of nonhuman primates in preclinical studies to advance the development of effective AIDS vaccine candidates and to advance development of effective topical microbicides and other prevention modalities or immune-based therapies. The NIAID Simian Vaccine Evaluation Unit (SVEU) contracts shall provide nonhuman primate resources that primarily support preclinical evaluation of AIDS vaccines. The SVEUs conduct studies in support of vaccines being developed by a wide range of investigators. These studies complement NIAID-supported basic vaccine research and vaccine evaluation studies funded through R01 (investigator-initiated research) grants, HIVRAD (HIV Vaccine Research and Design Program) grants, IPCAVD (Integrated Preclinical-Clinical AIDS Vaccine Development) grants, and NHP Consortium awards. The SVEUs also perform studies of candidate vaccines offered by companies or other researchers.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Evaluation of the Immunogenicity and Efficacy of a Non-Integrating Integrase-Defective Lentiviral Vector (IDLV)
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批准号:10703333
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项目类别:
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资助金额:$0.27万
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财政年份:2016
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负责人:HANNE ELYARD
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依托单位:
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批准号:9144274
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项目类别:
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资助金额:$65.14万
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财政年份:2015
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负责人:HANNE ELYARD
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依托单位:
Task C32: Model Refinement in Pig-Tailed Macaques to AssessTherapeutics for Chlamydia trachomatis
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批准号:9266256
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项目类别:
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资助金额:$70.69万
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财政年份:2015
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负责人:HANNE ELYARD
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依托单位:
Task C29: Filovirus Vaccination Studies in Non-Human Primates
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批准号:9200942
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项目类别:
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资助金额:$52.86万
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财政年份:2014
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负责人:HANNE ELYARD
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依托单位:
Task Order C25: Filovirus Vaccination Studies in NHPs
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批准号:8935346
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项目类别:
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资助金额:$2.17万
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财政年份:2010
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负责人:HANNE ELYARD
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依托单位:
海外基金