Photoprotection by vitamin D and analogs

到目前为止的发现和拟议的研究表明，皮肤中的维生素D化合物在保护皮肤免受阳光伤害方面具有内在作用。由于阳光暴晒，皮肤中维生素D化合物的浓度会增加，这可能会提供保护，防止进一步的紫外线损害，这与皮肤外层的色素沉着增加和厚度增加大致相同。此外，这些研究旨在测试对血清钙影响最小的维生素D化合物是否仍可与防晒霜或保湿霜一起局部使用，以增加防晒效果。由于澳大利亚的皮肤癌发病率是世界上最高的，这将具有重大的健康和经济价值。

The discoveries made to date and the proposed studies point to an intrinsic role for vitamin D compounds in skin in providing protection from sun damage. As a result of sun exposure, increased concentrations of vitamin D compounds in skin will be generated and this is likely to provide protection against further UV damage, in much the same way as increased pigmentation and increased thickness of the outer layer of skin. Furthermore, the studies are designed to test whether vitamin D compounds which have minimal effects on serum calcium, could nevertheless be used topically in association with a sunscreen or moisturizer to add to sun protection. As Australia has the highest skin cancer rates in the world, this would be of significant health and economic value.