Plasticity of cone bipolar cells in retinas with visual dysfunction.

视觉功能障碍视网膜中视锥双极细胞的可塑性。

• 批准号: nhmrc : 567031
• 负责人: Dr Sammy Chi Sam Lee
• 金额: $ 21.89万
• 依托单位: The University of Sydney
• 依托单位国家: 澳大利亚
• 项目类别: Early Career Fellowships
• 财政年份: 2009
• 资助国家: 澳大利亚
• 起止时间: 2009-01-01 至 2014-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/plasticity-cone-bipolar-visual-dysfunction/116027
• 关键词: Plasticity; cone; bipolar; cells; retinas

Advances in stem cell research and gene therapy have shown great promise in their application to eye disorders that lead to blindness. This project will examine the capacity of nerve cells in the eye to remodel in the presence of visual dysfunction and subsequent recovery after gene therapy. The results from this study will therefore benefit current approaches employed for the reestablishment of vision in eye diseases.

干细胞研究和基因治疗的进展在治疗导致失明的眼部疾病方面显示出了巨大的前景。该项目将检查眼睛神经细胞在视觉功能障碍的情况下重塑的能力以及基因治疗后的恢复能力。因此，这项研究的结果将有利于目前用于眼部疾病重建视力的方法。