Prediction of fracture by clinico-genetic profiling

随着年龄的增长，骨质流失是导致骨质疏松和骨折的主要原因。骨质流失因人而异，我们不确定原因。我想找出导致骨质流失的因素，然后利用这些知识来识别那些有骨质流失高风险的人，以便及早预防。我未来5年的目标是创建一种新的临床遗传学模型，用于评估骨质流失率，并预测个体骨折的风险。

The loss of bone with advancing age is the main cause of osteoporosis and bone fracture. Bone loss is highly variable between individuals, and we are not sure why. I want to find out factors that contribute to bone loss, and then use this knowledge to identify individuals at high risk of excessive bone loss for early prevention. My goal over the next 5 years is to create a new clinico-genetic model for assessing the rate of bone loss, and predicting the risk of fracture for an individual.