Prenatal origins and health outcomes of male reproductive congenital anomalies diagnosed at birth and testicular cancer in adulthood

出生时诊断的男性生殖先天异常和成年睾丸癌的产前起源和健康结局

• 批准号: nhmrc : 1047263
• 负责人: Dr Gavin Pereira
• 金额: $ 15.63万
• 依托单位: Australian National University
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2013
• 资助国家: 澳大利亚
• 起止时间: 2013-01-01 至 2016-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/prenatal-origins-health-cancer-adulthood/111923
• 关键词: Prenatal; origins; health; outcomes; male

There is growing concern in increasing male reproductive congenital anomalies diagnosed at birth & testicular cancer in adulthood. Research suggests these conditions share a common origin due to disruption in the release of male hormones in early pregnancy. This study will use a novel method of record-linkage to investigate maternal and infant risk factors and their combined effect on male reproductive disorders at birth and later in life; & assess long-term health and fertility of these males.

人们越来越关注出生时诊断出的男性生殖先天性异常和成年后睾丸癌的增加。研究表明，这些情况有一个共同的根源，即怀孕早期雄性激素释放中断。这项研究将使用一种新的记录关联方法来调查孕产妇和婴儿的危险因素及其对出生时和以后生活中男性生殖疾病的综合影响；并评估这些男性的长期健康状况和生育能力。