Preventing Infections in Young Infants with Azithromycin in Labour (PreYIAL): a blinded placebo-controlled randomised controlled trial

分娩时使用阿奇霉素预防小婴儿感染 (PreYIAL)：一项盲法安慰剂对照随机对照试验

• 批准号: nhmrc : GNT1144111
• 负责人: A/Pr Fiona Russell
• 金额: $ 149.11万
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2018
• 资助国家: 澳大利亚
• 起止时间: 2018-01-01 至 无数据
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/preventing-infections-young-controlled-trial/1348583
• 关键词: Preventing; Infections; Young; Infants; Azithromycin

Approximately one million babies die from infection each year with almost all deaths occurring in poor countries. Many of these infections are acquired from the mother around labour. Skin infection rates are very high in Pacific island countries. Our study in Fiji will determine whether a single dose of antibiotic in labour reduces infant skin infections. We will also assess the effect on maternal and infant infection rates, and the carriage of common bacterial.

每年约有100万婴儿死于感染，几乎所有死亡都发生在贫穷国家。许多感染是从分娩前后的母亲那里获得的。太平洋岛屿国家的皮肤感染率非常高。我们在斐济的研究将确定在分娩时使用一剂抗生素是否会减少婴儿皮肤感染。我们亦会评估对母婴感染率的影响，以及常见细菌的携带情况。