Prophylactic antibiotics to prevent recurrent lower respiratory tract infections in children with neurological impairment (PARROT) study

预防性抗生素预防神经功能障碍儿童复发性下呼吸道感染（PARROT）研究

• 批准号: nhmrc : GNT1149332
• 负责人: A/Pr Ian Masters
• 金额: $ 119.35万
• 依托单位国家: 澳大利亚
• 项目类别: International Collaborations
• 财政年份: 2019
• 资助国家: 澳大利亚
• 起止时间: 2019-01-01 至 无数据
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/prophylactic-antibiotics-prevent-parrot-study/1348894
• 关键词: Prophylactic; antibiotics; prevent; recurrent; lower

We plan a randomised controlled trial to determine if 12 months of a type of antibiotics (compared to placebo) reduces hospitalisations in children with neurological impairment. Currently this group of children are recurrently hospitalised and some doctors use long term antibiotics but there is no high level evidence for this practice. The study will be undertaken in the UK and Australia and involve 474 children. The study will lead to better clinical care and inform guidelines.

我们计划进行一项随机对照试验，以确定12个月的一种抗生素（与安慰剂相比）是否会减少神经损伤儿童的住院率。目前，这组儿童经常住院，一些医生使用长期抗生素，但这种做法没有高水平的证据。这项研究将在英国和澳大利亚进行，涉及474名儿童。这项研究将导致更好的临床护理和指导方针。