Protein trafficking in inflammation and disease

炎症和疾病中的蛋白质运输

• 批准号: nhmrc : 1003021
• 负责人: Prof Jennifer Stow
• 金额: $ 58.71万
• 依托单位: The University of Queensland
• 依托单位国家: 澳大利亚
• 项目类别: Research Fellowships
• 财政年份: 2011
• 资助国家: 澳大利亚
• 起止时间: 2011-01-01 至 2016-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/protein-trafficking-inflammation-disease/108884
• 关键词: Protein; trafficking; inflammation; disease

Understanding the basic biology of cells will allow us to pinpoint key mechanisms and molecules that underpin multiple diseases and are targets for treatments. The broad aims of this research program include the development of new therapies for chronic inflammatory diseases, understanding how proteins are sorted and trafficked inside cells in processes that are essential to immunity and cancer biology, and identifying new intracellular targets to block bacterial invasion and infectious diseases.

了解细胞的基本生物学将使我们能够确定支持多种疾病的关键机制和分子，并成为治疗的目标。该研究计划的广泛目标包括开发慢性炎症性疾病的新疗法，了解蛋白质如何在免疫和癌症生物学所必需的过程中在细胞内进行分类和运输，并确定新的细胞内靶点以阻止细菌入侵和感染性疾病。