Re-EValuating the Inhibition of Stress Erosions (REVISE): Gastrointestinal bleeding prophylaxis in ICU

重新评估应力腐蚀的抑制（REVISE）：ICU 中的胃肠道出血预防

• 批准号: nhmrc : GNT1124675
• 负责人: A/Pr Adam Deane
• 金额: $ 295.52万
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2017
• 资助国家: 澳大利亚
• 起止时间: 2017-01-01 至 无数据
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/re-evaluating-inhibition-prophylaxis-icu/1347424
• 关键词: Re; EValuating; Inhibition; Stress; Erosions

Around 50,000 patients in Australian Intensive Care Units receive a drug called pantoprazole each year with the aim of preventing bleeding from the gut. Recent research suggests this practice is ineffective and may harm patients by increasing their risk of serious infections. We will perform a definitive study to determine whether the widespread use of pantoprazole is beneficial or harmful.

澳大利亚重症监护病房每年约有5万名患者接受一种名为潘托拉唑的药物治疗，目的是防止肠道出血。最近的研究表明，这种做法是无效的，可能会增加患者严重感染的风险，从而对患者造成伤害。我们将进行一项明确的研究，以确定潘托拉唑的广泛使用是有益的还是有害的。