The consequence of Plasmodium falciparum culturing conditions on tolerance to anti-malarial drugs.
The consequence of Plasmodium falciparum culturing conditions on tolerance to anti-malarial drugs.
批准号:
nhmrc : 1150359
负责人:
金额:
$5.9万
依托单位:
依托单位国家:
澳大利亚
项目类别:
Postgraduate Scholarships
财政年份:
2018
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2018-01-01 至 2020-12-31
中文摘要
在实验室培养引起疟疾的寄生虫对研究至关重要。将研究如何培养寄生虫的变化对寄生虫的影响。我们特别感兴趣的是不同的条件如何影响寄生虫对疟疾药物的反应。通过了解环境参数如何影响寄生虫及其对抗疟疾药物的反应,我们将提高对疟疾耐药性的认识,从而设计出更好的药物。
英文摘要
Culturing the parasite that causes malaria in the laboratory is essential for research. Variations in how the parasites are cultured will be investigated for their effect on the parasite. We are particularly interested in how different conditions affect the parasites’ response to malaria drugs. By understanding how environmental parameters impact on the parasites and their response to anti-malarial drugs, we will improve our understanding of drug resistance to malaria, thus design better drugs.
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