The development of a loop-mediated isothermal amplification (LAMP) assay for the detection of Strongyloides stercoralis in the stool.

开发用于检测粪便中粪类圆线虫的环介导等温扩增（LAMP）测定法。

• 批准号: nhmrc : 1040002
• 负责人: Dr Matthew Watts
• 金额: $ 8.5万
• 依托单位: The University of Sydney
• 依托单位国家: 澳大利亚
• 项目类别: Postgraduate Scholarships
• 财政年份: 2012
• 资助国家: 澳大利亚
• 起止时间: 2012-01-01 至 2015-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/development-loop-mediated-stercoralis-stool/111318
• 关键词: development; loop; mediated; isothermal; amplification

A new test will be developed for the detection of the worm, Strongyloides stercoralis in the stool. S. stercoralis infects millions of people worldwide and occurs in the north of Australia. It can occasionally cause a ‘hyperinfection’ with fatal consequences. The test is based on the DNA detection method, loop-mediated isothermal amplification (LAMP), which can be performed using simple equipment. The aim will be to make this test as easy possible to perform and to evaluate its effectiveness.

将开发一种新的测试来检测粪便中的粪类圆线虫。粪圆线虫感染了全世界数百万人，发生在澳大利亚北部。它有时会导致“过度感染”，从而造成致命的后果。该测试基于DNA检测方法——环介导等温扩增（LAMP），可以使用简单的设备进行。目的是使该测试尽可能容易执行并评估其有效性。