The effect of anti-fibrinolytic drugs on blood-brain barrier integrity and the immune response in traumatic brain injury

抗纤溶药物对脑外伤血脑屏障完整性和免疫反应的影响

• 批准号: nhmrc : 1126636
• 负责人: A/Pr Huyen Tran
• 金额: $ 59.47万
• 依托单位: Monash University
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2017
• 资助国家: 澳大利亚
• 起止时间: 2017-01-01 至 2020-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/effect-anti-fibrinolytic-brain-injury/947827
• 关键词: effect; anti; fibrinolytic; drugs; blood

This project aims to determine how a well known anti-fibrinolytic drug can improve the immune response and reduced blood brain barrier disruption following traumatic brain injury. We will also be testing additional drugs we have developed as well as a novel drug delivery system that better targets drugs to the damaged brain.

该项目旨在确定一种众所周知的抗纤溶药物如何改善创伤性脑损伤后的免疫反应并减少血脑屏障破坏。我们还将测试我们开发的其他药物以及一种新的药物输送系统，该系统可以更好地将药物靶向受损的大脑。