The integrated assessment of cardiac function and synchrony, and its clinical implications in cardiac pacing.

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Current techniques for assessing cardiac function are limited. We seek firstly to help prove the accuracy of new techniques to assess cardiac function using novel echocardiographic (cardiac ultrasound) tools. We will then apply these tools to patients with severe heart failure who are receiving cardiac resynchronisation therapy - a new, potentially life-saving type of pacemaker - to maximise potential patient benefit. We will also use these tools to help optimise conventional pacemaker function.