The integration of high level clinical medicine, molecular genics, and cutting edge neuroimaging

我的目标是巩固我作为国际上领先的癫痫临床和转化研究人员的地位。我和我更广泛的团队的研究重点是高水平临床医学，分子遗传学和前沿神经影像学的整合，这是由临床相关的基础神经科学告知和加强。这种综合模型在癫痫领域是独一无二的。该奖学金将使我有机会扩展这一模式，并最佳地利用遗传学和成像方面快速发展的技术，这是临床神经科学中最重要和最富有成效的两个领域。我在这方面处于独特的国际地位，因为我在过去二十年中精心收集和描述了临床队列，与组成我个人研究团队的杰出临床和基础科学研究人员以及我领导的更广泛的团队合作，由NHMRC项目资助。该奖学金将为我们提供额外的核心遗传专业知识，使我们能够进一步解决癫痫复杂遗传学这一具有挑战性的问题。我希望提高我的小组作为癫痫创新和临床相关研究国际中心的影响力和声誉。这将提高澳大利亚在健康和医学研究方面的声誉。

I aim to cement my place as the leading clinical and translational researcher in epilepsy internationally. My research and that of my wider group is focused on the integration of high level clinical medicine, molecular genetics and cutting-edge neuroimaging, which is informed and enhanced by clinically relevant basic neuroscience. This integrative model is unique in the epilepsy field. The Fellowship will give me the opportunity to expand this model and optimally utilize the rapidly developing technologies in genetics and imaging which are the two most important and productive fields in clinical neuroscience. I am in a unique international position to do this because of the clinical cohorts that I have meticulously collected and characterized over the last two decades, working with the remarkable group of clinical and basic science investigators that form my personal research team, and the wider group that I head, supported by an NHMRC Program Grant. This Fellowship will provide for a major injection of additional core genetic expertise to take us up to the next level necessary to crack the challenging problem of the complex genetics of the epilepsies. I wish to increase the impact and reputation of my wider group as the International Centre for innovative and clinically relevant research in epilepsy. This will enhance the reputation of Australia as a place of excellence in health and medical research.