Appendicitis, Protection again Colitis and the Role of Colonic Regulatory T Cells

阑尾一直被认为是一个无用的器官，然而，有证据表明切除阑尾可以降低患炎症性肠病的风险。我们已经证明，这可能是由于肠道免疫调节的改变。该项目计划探索导致这种免疫调节改变的机制。随着从这些研究中获得致病的具体因素的知识，将会有更有效和更有针对性的治疗方案。

The appendix has been regarded as a useless organ, however, there are evidence showing its removal reduces the risk of developing inflammatory bowel disease. We have shown that this may be due to altered intestinal immune regulation. The project plans to explore the mechanisms responsible for this altered immune regulation. With knowledge of specific elements of disease causation gained from these studies, more effective and targeted treatment options will become available.