Appendicitis, Protection again Colitis and the Role of Colonic Regulatory T Cells

阑尾炎、结肠炎的再次保护和结肠调节性 T 细胞的作用

• 批准号: nhmrc : 1039796
• 负责人: Miss Annie Luo
• 金额: $ 4.49万
• 依托单位: The University of New South Wales
• 依托单位国家: 澳大利亚
• 项目类别: Postgraduate Scholarships
• 财政年份: 2012
• 资助国家: 澳大利亚
• 起止时间: 2012-01-01 至 2014-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/appendicitis-protection-colitis-t-cells/111306
• 关键词: Appendicitis; Protection; again; Colitis; Role

The appendix has been regarded as a useless organ, however, there are evidence showing its removal reduces the risk of developing inflammatory bowel disease. We have shown that this may be due to altered intestinal immune regulation. The project plans to explore the mechanisms responsible for this altered immune regulation. With knowledge of specific elements of disease causation gained from these studies, more effective and targeted treatment options will become available.

阑尾一直被认为是一个无用的器官，然而，有证据表明，它的切除可以降低患炎症性肠病的风险。我们已经表明，这可能是由于改变肠道免疫调节。该项目计划探索这种改变免疫调节的机制。随着从这些研究中获得的疾病病因的具体要素的知识，将提供更有效和更有针对性的治疗方案。