Two recently identified calcium transporters in lactation and during mammary epithelial cell apoptosis.
最近发现了两种在哺乳期和乳腺上皮细胞凋亡过程中的钙转运蛋白。
基本信息
- 批准号:nhmrc : 631347
- 负责人:
- 金额:$ 31.01万
- 依托单位:
- 依托单位国家:澳大利亚
- 项目类别:NHMRC Project Grants
- 财政年份:2010
- 资助国家:澳大利亚
- 起止时间:2010-01-01 至 2013-12-31
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
The transport of calcium into milk is a key event in human health. In addition to its importance in neonatal nutrition, the way breast cells regulate calcium also has implications in breast cancer, as well as the modification of proteins important in immunity, and the activity of biopharmaceuticals. This grant will determine how two specific calcium transporters regulate calcium levels in the breast and their respective roles in cellular processes important in normal function and in disease.
钙在牛奶中的运输是人类健康的关键事件。除了在新生儿营养中的重要性外,乳腺细胞调节钙的方式也对乳腺癌、免疫中重要的蛋白质的修饰以及生物药物的活性有影响。这项资助将确定两种特定的钙转运蛋白如何调节乳腺中的钙水平,以及它们各自在正常功能和疾病中重要的细胞过程中的作用。
项目成果
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