Assessment of remote ischemic conditioning on post-cardiac arrest myocardial dysfunction by magnetic resonance imaging, invasive coronary hemodynamic measurements and markers of inflammation

通过磁共振成像、侵入性冠状动脉血流动力学测量和炎症标志物评估心脏骤停后心肌功能障碍的远程缺血调节

• 批准号: nhmrc : 1090302
• 负责人: Dr Dion Stub
• 金额: $ 17.73万
• 依托单位: Baker IDI Heart and Diabetes Institute
• 依托单位国家: 澳大利亚
• 项目类别: Early Career Fellowships
• 财政年份: 2015
• 资助国家: 澳大利亚
• 起止时间: 2015-01-01 至 2018-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/assessment-remote-ischemic-markers-inflammation/519277
• 关键词: Assessment; remote; ischemic; conditioning; post

Cardiac arrest and heart attack continue to cause unacceptably high mortality and morbidity. Even following successful resuscitation many people do not recover due to the inflammation caused by a lack of blood flow. We will investigate remote ischemic conditioning, utilizing a combination of world class imaging with heart MRI, flow monitors directly in heart arteries and markers of inflammation, We aim to determine the impact and recovery to the heart, brain and circulation of this new therapy.

心脏骤停和心脏病发作继续造成令人无法接受的高死亡率和发病率。即使在成功复苏之后，许多人也无法恢复，因为缺乏血液流动引起的炎症。我们将研究远程缺血条件，利用世界级的心脏MRI成像，心脏动脉血流监测仪和炎症标志物的组合，我们的目标是确定这种新疗法对心脏，大脑和循环的影响和恢复。