Australia Fellowship

麦凯教授通过这次澳大利亚联谊会，提议通过探索这些关于炎症以及饮食和胃肠道微生物区系的作用的激进新想法，获得关于免疫反应的新知识。此外，他希望通过整合新的强大的技术和方法来产生生物疗法，从而开发出治疗人类疾病的新方法。最后，转基因小鼠将在这一过程中发挥关键作用，并将使发现新一代药物成为可能，这在几年前是不可能的。澳大利亚联谊会将利用相当多的跨学科互动，在医学研究中产生强有力的新方向。例如，有相当多的证据，但对新陈代谢如何调节免疫系统，或干细胞在与炎症相关的组织重塑中的作用，或免疫系统与癌症之间的微妙相互作用，有相当多的证据，但了解很少。

Prof Mackay, through this Australia Fellowship, proposes to gain new knowledge on immune responses, by exploring these radical new ideas on inflammation and the role of diet and gastro-intestinal microflora. In addition, he hopes to develop new treatments for human diseases, by integrating new and powerful technologies and approaches for the generation of bio-therapeutics. Finally, genetically engineered mice will be pivotal in this process, and will enable the discovery of a new generation of medicines not possible a couple of years ago. The Australia Fellowship will draw on considerable cross-discipline interactions, to produce powerful new directions in medical research. For instance, there is considerable evidence, but poor understanding, of how the immune system is regulated by metabolism or the role of stem cells in tissue remodelling associated with inflammation, or the delicate interplay between the immune system and cancers.