Australia Fellowship

癌症免疫学已成为肿瘤学的一门基础学科，从大量患者研究中获得的大量新数据揭示了免疫反应在患者预后中的重要性。史密斯教授已经建立了大量的工作表明，免疫反应是肿瘤发展的速度限制。他之前的基础性工作为开展新的研究提供了一个平台，这些研究将大大提高我们对控制肿瘤起始、生长和转移的各种免疫机制的理解的复杂性。史密斯教授澳大利亚奖学金的主要目标是了解为什么有些肿瘤可能受到免疫反应的控制，而另一些则显然不是。他已经建立了小鼠癌症模型，这些问题可以第一次直接解决。

Cancer immunology has emerged as a fundamental discipline of oncology and overwhelming new data from large patient studies reveals the importance of the immune reaction in patient prognosis. Professor Smyth has established a large body of work indicating that the immune reaction is rate limiting for the development of tumours. His previous fundamental work forms a platform to launch new studies that will greatly increase the sophistication with which we understand the various immune mechanisms that control tumour initiation, growth and metastases. It is a major goal of Professor Smyth’s Australia Fellowship to understand why some tumours may be controlled by the immune response while others are apparently not. He has established mouse models of cancer where these questions can be directly addressed for the first time.