BEST-Australia: A Phase II Study of Non-Endoscopic Screening for Barretts Oesophagus in Primary Care

巴雷特食管常见于胃灼热患者，并可能发展为食管癌。大多数食管癌病例是在晚期诊断出来的，当时生存的机会很低。目前巴雷特氏病只能通过内窥镜诊断。我们将测试非内窥镜海绵胶囊和新型实验室检查在早期检测巴雷特食管方面的有效性和可接受性。这有可能在一般实践中早期发现这种癌前病变。

Barrett's oesophagus is common in people with heartburn and may progress to oesophageal cancer. Most cases of oesophageal cancer are diagnosed at a late stage when chances of survival are poor. Currently Barrett's is only diagnosed by endoscopy. We will test how effective and acceptable a non-endoscopic sponge capsule and novel laboratory test is at detecting Barrett's oesophagus early. This could potentially enable early detection of this pre-cancerous condition in general practice.