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Imaging system for DNA, RNA and proteins

Imaging system for DNA, RNA and proteins
DNA、RNA 和蛋白质成像系统
批准号:
331038-2006
负责人:
Lemay, Guy
金额:
$10.93万
依托单位:
依托单位国家:
加拿大
项目类别:
Research Tools and Instruments - Category 1 (<$150,000)
财政年份:
2006
资助国家:
加拿大
项目状态:
已结题
起止时间:
2006-01-01 至 2007-12-31

项目摘要

项目成果

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中文摘要
翻译
所要求的设备是一个最先进的文件系统,以满足由CIHR或NSERC的运营赠款支持的研究计划的迫切需要。除了6名研究人员及其研究团队外,该设备还将提供给该部门的所有研究团队。包括研究生、博士后、技术人员和研究助理在内的40多人将定期使用该设备。此外,每年有超过25名本科生在我们的实验室进行研究,作为他们在微生物学和免疫学本科学习的一部分。作为一个文件系统本身,该设备节省时间,并在各种应用中增加灵敏度,放射性和非放射性。它还可以更容易地用更安全的非放射性替代品取代基于放射性同位素的方法。除了文件本身,该设备还可以对与我们各自研究项目相关的各种应用中的结果进行定量分析。微生物学和免疫学中细胞和分子生物学方法的发展要求对结果进行精确和可重复的定量分析,以得出可靠的结论。我们的成员定期发表的顶级科学期刊经常要求使用这种方法,并且所要求的设备可能是此类应用中最广泛接受的设备。因此,购买这些设备将大大提高我们的研究工作的生产力,这些研究工作由运营赠款支持,其中包括8个不同的目前正在进行的NSERC支持的研究赠款。
英文摘要
The equipment requested is a state-of-the-art documentation system that meets urgent needs for research programs supported by operating grants from the CIHR or the NSERC. In addition to the 6 investigators and their research teams, the equipment will be available to all research teams of the department. Over 40 people, including graduate students, postdocs, technicians and research assistants will be using this equipment on a routine basis. In addition, several undergraduate students, more than 25 every year, are performing research in our laboratories as part of their undergraduate studies in microbiology and immunology. As a documentation system per se, the equipment saves time and gives added senstivity in various applications, radioactive and nonradioactive alike. It also allows easier replacement of radioisotope-based approaches by safer nonradioactive alternatives. In addition to documentation per se, the equipment allows quantitative analysis of the results in various applications pertinent to our respective research programs. Development of cellular and molecular biology approaches in microbiology and immunology requests precise and reproductible quantitative analysis of results, in order to generate solid conclusions. Such approaches are routinely requested by the top scientific journals in which our members are regularly publishing, and the requested equipment is probably the most widely accepted in such applications. Acquisition of this equipment will thus considerably improve the productivity of our research supported by operating grants, including 8 different currently active NSERC-supported research grants.
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Molecular dissection studies of mammalian reovirus proteins using reverse genetics.
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  • 项目类别:
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    2018
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