Micromechanical testing system

微机械测试系统

• 批准号: 345387-2007
• 负责人: Dumas, Genevieve
• 金额: $ 6.51万
• 依托单位: Queen's University
• 依托单位国家: 加拿大
• 项目类别: Research Tools and Instruments - Category 1 (<$150,000)
• 财政年份: 2006
• 资助国家: 加拿大
• 起止时间: 2006-01-01 至 2007-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=326259
• 关键词: Micromechanical; testing; system

The requested equipment will create a new multi-user facility and allow us to expand our current research  and make new advances in determining properties of biological tissues -bone, cartilage, prostate- and biomaterials at the microscopic level. It will be used to support our graduate programs in Mechanical and Materials Engineering, Chemical Engineering and Computing Science. The requested equipment consists in a) a mechanical system to test small biological samples (Biosyntech Micromechanical System A400.25) and b) a microscope to dissect and prepare the samples and well as examine them. The research programs that will be using the requested equipment are: a) Mechanical characterization of bone tissue: the objective is to investigate the relationships between bone microstructure, tissue properties and strength for better fracture prediction and treatment. b) Tissue engineering: one of the examples of this research has a specific focus on the effects of mechanical stimulation to enhance the synthesis and subsequent properties of developed cartilage tissue. c) Characterization of prostate tissues:  The objective of this research is to develop a scientific basis for better diagnosis techniques of prostate cancer. Specifically, the differences of cell geometry and topology between cancerous and normal tissue within the prostate are examined.

所要求的设备将创建一个新的多用户设施，并使我们能够扩大我们目前的研究范围，并在微观层面上确定生物组织-骨、软骨、前列腺-和生物材料的性质方面取得新的进展。它将用于支持我们在机械与材料工程、化学工程和计算科学方面的研究生课程。所要求的设备包括a)测试小型生物样本的机械系统(BioSyntech微机械系统A400.25)和b)解剖和准备样本并对其进行检查的显微镜。将使用所需设备的研究项目是：a)骨组织的机械特性：目的是研究骨微结构、组织特性和强度之间的关系，以便更好地预测和治疗骨折。B)组织工程学：这项研究的一个例子特别侧重于机械刺激的效果，以增强发达的软骨组织的合成和随后的特性。C)前列腺癌组织的特征：这项研究的目的是为前列腺癌更好的诊断技术开发科学基础。具体地说，研究了前列腺癌组织和正常组织之间细胞几何和拓扑结构的差异。