Brain Pathways Underlying Vulnerability to Drug Relapse

药物复发的大脑通路

• 批准号: nhmrc : 510778
• 负责人: A/Pr Christopher Dayas
• 金额: $ 27.79万
• 依托单位: The University of Newcastle
• 依托单位国家: 澳大利亚
• 项目类别: NHMRC Project Grants
• 财政年份: 2008
• 资助国家: 澳大利亚
• 起止时间: 2008-01-01 至 2013-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/brain-pathways-underlying-drug-relapse/78503
• 关键词: Brain; Pathways; Underlying; Vulnerability; Drug

Addiction to drugs is a major health and social burden for Australian society. Once addiction is established, prevention of relapse is the most significant obstacle to successful treatment. Unfortunately, efficacious pharmaceutical options to treat relapse are lacking. By employing an animal model of relapse that accurately reflects drug taking in humans the proposed project aims to advance our understanding of the brain mechanism underlying addiction.

吸毒成瘾是澳大利亚社会的一个主要健康和社会负担。一旦成瘾，预防复发是成功治疗的最大障碍。不幸的是，缺乏治疗复发的有效药物选择。通过采用一种准确反映人类服药情况的动物复发模型，该项目旨在促进我们对成瘾背后的大脑机制的理解。