Cancer radiotherapy 2020: accounting for tumour deformation in real time to improve treatment outcome

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Tumours in lung and prostate cancer change shape during radiotherapy treatment. This is not accounted for in current care, compromising the therapeutic efficacy. We will develop the first radiotherapy system that can adjust the radiation beam in real time to follow the changing tumour shape. We will assess the performance of the system and quantify the clinical benefit. It is expected that clinical implementation of this technique will improve the cure rates and decrease the treatment toxicity.