Causal pathways from maternal obesity to pregnancy, perinatal & childhood health outcomes

孕产妇肥胖与妊娠、围产期的因果关系

• 批准号: nhmrc : 1068320
• 负责人: A/Pr Lynne Giles
• 金额: $ 51.72万
• 依托单位: The University of Adelaide
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2014
• 资助国家: 澳大利亚
• 起止时间: 2014-01-01 至 2016-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/causal-pathways-maternal-health-outcomes/455340
• 关键词: Causal; pathways; maternal; obesity; pregnancy

Overweight and obesity affects more than 50% of women entering pregnancy. There are well-documented risks of poor health outcomes associated with obesity during pregnancy. We will evaluate whether an antenatal dietary and lifestyle intervention among pregnant women who are overweight or obese, acts via metabolic, hormonal, and inflammatory pathways, in the contribution of maternal obesity to adverse pregnancy, perinatal and early childhood health outcomes.

超重和肥胖影响了50%以上的怀孕妇女。有充分的证据表明，怀孕期间肥胖与健康状况不佳有关。我们将评估超重或肥胖孕妇的产前饮食和生活方式干预是否通过代谢、激素和炎症途径起作用，在孕产妇肥胖对不良妊娠、围产期和幼儿健康结局的影响中起作用。