Cellular Modelling of Attention Deficit Hyperactivity Disorder (ADHD) Risk Genes

注意力缺陷多动障碍 (ADHD) 风险基因的细胞模型

• 批准号: nhmrc : 1146644
• 负责人: Dr Ziarih Hawi
• 金额: $ 50.26万
• 依托单位: Monash University
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2018
• 资助国家: 澳大利亚
• 起止时间: 2018-01-01 至 2021-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/cellular-modelling-attention-risk-genes/1320709
• 关键词: Cellular; Modelling; Attention; Deficit; Hyperactivity

Attention deficit hyperactivity disorder is a prevalent behavioural disorder affecting 7.4% of Australian children and adolescents. It has a strong genetic component with high heritability estimates (75–90%) comparable to other serious mental illness such as autism and schizophrenia. Identification and functional characterization of the genetic causes of this disorder will enhance our knowledge of its neurobiology and revolutionise the drug treatment of the disorder.

注意缺陷多动障碍是一种普遍的行为障碍，影响了7.4%的澳大利亚儿童和青少年。它有很强的遗传成分，估计遗传率很高（75-90%），与自闭症和精神分裂症等其他严重精神疾病相当。这种疾病的遗传原因的识别和功能表征将增强我们对其神经生物学的认识，并彻底改变这种疾病的药物治疗。