Changes in protein glycosylation promote endometrial receptivity leading to successful implantation

~15%的夫妇不能生育。他们对生殖技术（如体外受精）的依赖在过去十年中增加了4倍。不孕的一个原因是子宫内膜（子宫内膜）不能让胚胎附着——这是建立健康妊娠的关键事件。目前还没有测试来评估子宫内膜是否能“接受”胚胎。我们将开发一种特殊的检测方法，并为不求助于体外受精的治疗提供基础。

~15% of couples are unable to have children. Their reliance on reproductive technologies (eg, IVF) has increased 4 fold over the past decade. One reason for infertility is that the lining of the uterus (endometrium) is not able to allow an embryo to attach – a key event in establishing healthy pregnancy. There is no test to assess whether the endometrium is ‘receptive’ to an embryo. We will develop special assays for a test and provide a basis for treatment without recourse to IVF.