Characterisation of the dynamics of the mucosal immune response in the urinary tract in response to pathogenic bacteria

泌尿道粘膜免疫反应对病原菌的动态表征

• 批准号: nhmrc : 1052464
• 负责人: Dr Alison Carey
• 金额: $ 20.95万
• 依托单位: Queensland University of Technology
• 依托单位国家: 澳大利亚
• 项目类别: Early Career Fellowships
• 财政年份: 2013
• 资助国家: 澳大利亚
• 起止时间: 2013-01-01 至 2018-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/characterisation-dynamics-mucosal-pathogenic-bacteria/112276
• 关键词: Characterisation; dynamics; mucosal; immune; response

Urinary tract infections are among the most common infectious diseases in humans, with approximately 40% of adult women having experienced at least one. I aim to characterise and compare the dynamics of the innate immune response in the urinary tract, in response to uropathogens and characterise bacterial factors affecting such responses. Understanding immune function provides important new understanding into these disease processes that may result in the development of new treatment approaches.

尿路感染是人类最常见的传染病之一，大约40%的成年女性至少经历过一次。我的目标是描述和比较尿路中对尿路病原体的先天性免疫反应的动态，并描述影响这种反应的细菌因素。了解免疫功能提供了对这些疾病过程的重要新理解，这可能导致新的治疗方法的发展。