Characterising neurobiological abnormalities in Cannabis Use Disorders

大麻使用障碍的神经生物学异常特征

• 批准号: nhmrc : 1130079
• 负责人: A/Pr Antonio Verdejo-Garcia
• 金额: $ 50.08万
• 依托单位: University of Wollongong
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2017
• 资助国家: 澳大利亚
• 起止时间: 2017-01-01 至 2021-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/characterising-neurobiological-abnormalities-use-disorders/948514
• 关键词: Characterising; neurobiological; abnormalities; Cannabis; Use

Severe Cannabis Use Disorders cause significant harms to quality of life and outcomes including mental health, cognition, motivation and general well being. We will characterise, for the first time, the neuroadaptations associated with cannabis dependence relative to regular use via advanced imaging techniques and examine links between neural alterations and quality of life. This study will help to identify new treatment targets and develop a new neural model of cannabis addiction.

严重的大麻使用障碍会对生活质量和结果造成重大损害，包括心理健康，认知，动机和一般福祉。我们将首次通过先进的成像技术研究与大麻依赖相关的神经适应性，并研究神经改变与生活质量之间的联系。这项研究将有助于确定新的治疗靶点，并开发新的大麻成瘾神经模型。