Identification and characterization of potential drug-pollutant interactions
潜在药物-污染物相互作用的识别和表征
基本信息
- 批准号:311900-2005
- 负责人:
- 金额:$ 2.44万
- 依托单位:
- 依托单位国家:加拿大
- 项目类别:Discovery Grants Program - Individual
- 财政年份:2006
- 资助国家:加拿大
- 起止时间:2006-01-01 至 2007-12-31
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
No summary - Aucun sommaire
没有总结 - Aucun sommaire
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Haddad, Sami其他文献
The Role of Extracellular Binding Proteins in the Cellular Uptake of Drugs: Impact on Quantitative In Vitro-to-In Vivo Extrapolations of Toxicity and Efficacy in Physiologically Based Pharmacokinetic-Pharmacodynamic Research
- DOI:
10.1002/jps.24571 - 发表时间:
2016-02-01 - 期刊:
- 影响因子:3.8
- 作者:
Poulin, Patrick;Burczynski, Frank J.;Haddad, Sami - 通讯作者:
Haddad, Sami
Impact of Extensive Plasma Protein Binding on the In Situ Hepatic Uptake and Clearance of Perampanel and Fluoxetine in Sprague Dawley Rats
- DOI:
10.1016/j.xphs.2020.07.003 - 发表时间:
2020-10-01 - 期刊:
- 影响因子:3.8
- 作者:
Bteich, Michel;Poulin, Patrick;Haddad, Sami - 通讯作者:
Haddad, Sami
Development of physiologically based toxicokinetic models for improving the human indoor exposure assessment to water contaminants: Trichloroethylene and trihalomethanes
- DOI:
10.1080/15287390600631789 - 发表时间:
2006-12-01 - 期刊:
- 影响因子:2.6
- 作者:
Haddad, Sami;Tardif, Ginette-Charest;Tardif, Robert - 通讯作者:
Tardif, Robert
A new guidance for the prediction of hepatic clearance in the early drug discovery and development from the in vitro-to-in vivo extrapolation method and an approach for exploring whether an albumin-mediated hepatic uptake phenomenon could be present under in vivo conditions
- DOI:
10.1016/j.xphs.2021.04.002 - 发表时间:
2021-06-18 - 期刊:
- 影响因子:3.8
- 作者:
Poulin, Patrick;Haddad, Sami - 通讯作者:
Haddad, Sami
PHYSIOLOGICALLY-BASED PHARMACOKINETIC (PBPK) MODELS IN TOXICITY TESTING AND RISK ASSESSMENT
- DOI:
10.1007/978-1-4614-3055-1_6 - 发表时间:
2012-01-01 - 期刊:
- 影响因子:0
- 作者:
Lipscomb, John C.;Haddad, Sami;Krishnan, Kannan - 通讯作者:
Krishnan, Kannan
Haddad, Sami的其他文献
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{{ truncateString('Haddad, Sami', 18)}}的其他基金
Advancing knowledge and developping mechanistic quantitative tools for in vitro-in vivo extrapolations in pharmacokinetics and toxicokinetics
增进知识并开发药代动力学和毒代动力学体外体内外推的机械定量工具
- 批准号:
RGPIN-2020-05251 - 财政年份:2022
- 资助金额:
$ 2.44万 - 项目类别:
Discovery Grants Program - Individual
Advancing knowledge and developping mechanistic quantitative tools for in vitro-in vivo extrapolations in pharmacokinetics and toxicokinetics
增进知识并开发药代动力学和毒代动力学体外体内外推的机械定量工具
- 批准号:
RGPIN-2020-05251 - 财政年份:2021
- 资助金额:
$ 2.44万 - 项目类别:
Discovery Grants Program - Individual
Advancing knowledge and developping mechanistic quantitative tools for in vitro-in vivo extrapolations in pharmacokinetics and toxicokinetics
增进知识并开发药代动力学和毒代动力学体外体内外推的机械定量工具
- 批准号:
RGPIN-2020-05251 - 财政年份:2020
- 资助金额:
$ 2.44万 - 项目类别:
Discovery Grants Program - Individual
In vitro-in vivo extrapolations and physiologically-based pharmacokinetic modeling: Predicting permeability, clearance, metabolic interactions and interindivual variability from in vitro data
体外-体内外推和基于生理学的药代动力学模型:根据体外数据预测渗透性、清除率、代谢相互作用和个体间差异
- 批准号:
RGPIN-2015-05577 - 财政年份:2019
- 资助金额:
$ 2.44万 - 项目类别:
Discovery Grants Program - Individual
In vitro-in vivo extrapolations and physiologically-based pharmacokinetic modeling: Predicting permeability, clearance, metabolic interactions and interindivual variability from in vitro data
体外-体内外推和基于生理学的药代动力学模型:根据体外数据预测渗透性、清除率、代谢相互作用和个体间差异
- 批准号:
RGPIN-2015-05577 - 财政年份:2018
- 资助金额:
$ 2.44万 - 项目类别:
Discovery Grants Program - Individual
In vitro-in vivo extrapolations and physiologically-based pharmacokinetic modeling: Predicting permeability, clearance, metabolic interactions and interindivual variability from in vitro data
体外-体内外推和基于生理学的药代动力学模型:根据体外数据预测渗透性、清除率、代谢相互作用和个体间差异
- 批准号:
RGPIN-2015-05577 - 财政年份:2017
- 资助金额:
$ 2.44万 - 项目类别:
Discovery Grants Program - Individual
In vitro-in vivo extrapolations and physiologically-based pharmacokinetic modeling: Predicting permeability, clearance, metabolic interactions and interindivual variability from in vitro data
体外-体内外推和基于生理学的药代动力学模型:根据体外数据预测渗透性、清除率、代谢相互作用和个体间差异
- 批准号:
RGPIN-2015-05577 - 财政年份:2016
- 资助金额:
$ 2.44万 - 项目类别:
Discovery Grants Program - Individual
In vitro-in vivo extrapolations and physiologically-based pharmacokinetic modeling: Predicting permeability, clearance, metabolic interactions and interindivual variability from in vitro data
体外-体内外推和基于生理学的药代动力学模型:根据体外数据预测渗透性、清除率、代谢相互作用和个体间差异
- 批准号:
RGPIN-2015-05577 - 财政年份:2015
- 资助金额:
$ 2.44万 - 项目类别:
Discovery Grants Program - Individual
Identification of drug-pollutant interactions and refining predictions of interindividual variability in pollutant toxicokinetics
药物-污染物相互作用的鉴定和污染物毒代动力学个体间变异性的精确预测
- 批准号:
311900-2010 - 财政年份:2014
- 资助金额:
$ 2.44万 - 项目类别:
Discovery Grants Program - Individual
Identification of drug-pollutant interactions and refining predictions of interindividual variability in pollutant toxicokinetics
药物-污染物相互作用的鉴定和污染物毒代动力学个体间变异性的精确预测
- 批准号:
311900-2010 - 财政年份:2013
- 资助金额:
$ 2.44万 - 项目类别:
Discovery Grants Program - Individual
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