Micropeptides as a tool for intracellular signalling and regulation in higher eukaryotes

微肽作为高等真核生物细胞内信号传导和调节的工具

• 批准号: 238940-2006
• 负责人: Pellegrini, Luca
• 金额: $ 2.06万
• 依托单位: Université Laval
• 依托单位国家: 加拿大
• 项目类别: Discovery Grants Program - Individual
• 财政年份: 2007
• 资助国家: 加拿大
• 起止时间: 2007-01-01 至 2008-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=361113
• 关键词: Micropeptides; tool; intracellular; signalling; regulation

A large number of micropeptides have been found in the cytoplasm and their potential structural ability to regulate intracellular signal transduction exists. However, their participation in this process is still largely unexplored. This study will investigate the function of micropeptides of mitochondrial origin, thereby addressing the question of whether micropeptides, either produced by the cell as part of protein catabolism or not, have signalling and/or regulatory ability inside the cell.

在细胞质中发现了大量的微肽，它们具有调节细胞内信号转导的潜在结构能力。然而，她们对这一进程的参与在很大程度上仍未得到探讨。这项研究将调查线粒体来源的微肽的功能，从而解决的问题，无论是由细胞产生的蛋白质catenase的一部分或没有，有信号和/或调节能力的细胞内的微肽。