The neural organization of person-based semantic knowledge in young and older adults

年轻人和老年人基于人的语义知识的神经组织

• 批准号: 340937-2007
• 负责人: Joubert, Sven
• 金额: $ 1.09万
• 依托单位: Université de Montréal
• 依托单位国家: 加拿大
• 项目类别: Discovery Grants Program - Individual
• 财政年份: 2007
• 资助国家: 加拿大
• 起止时间: 2007-01-01 至 2008-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=362328
• 关键词: neural; organization; person; based; semantic

How do we recognize and identify people we know? What is the neural organization underlying the knowledge we have about familiar people? Identifying people we know is a fundamental determinant of social interaction. It modulates our ability to interact with other people and to function normally in society.   The first part of this research project will be to use functional MRI, a neuroimaging method used to measure brain activity while the participant is performing a cognitive task, to investigate the brain regions that are activated during the processing of the faces and voices of famous people and unknown people. This will allow investigating what areas of the brain are involved in storing biographical information about people we know.   The second part of this research project will be interested in determining if the neural architecture underlying this type of knowledge changes during the course of aging, and if so how it changes. The aim will be to determine whether the cerebral organization of semantic memory undergoes the same changes as other memory systems that are more vulnerable to aging. Taken together, this research program will contribute to understanding the neural correlates of familiar person recognition in young and older adults.

我们如何识别和识别我们认识的人？我们对熟悉的人的了解背后的神经组织是什么？识别我们认识的人是社会交往的基本决定因素。它调节我们与他人互动的能力，以及在社会中正常发挥作用的能力。 该研究项目的第一部分将使用功能性MRI，这是一种神经成像方法，用于测量参与者在执行认知任务时的大脑活动，以调查在处理名人和陌生人的面孔和声音时激活的大脑区域。这将有助于研究大脑的哪些区域参与存储我们认识的人的传记信息。 该研究项目的第二部分将有兴趣确定这种类型的知识背后的神经结构是否在衰老过程中发生变化，如果是这样，它是如何变化的。其目的是确定语义记忆的大脑组织是否会像其他更容易衰老的记忆系统一样经历同样的变化。总之，这项研究计划将有助于了解年轻人和老年人熟悉的人识别的神经相关性。