Statistical topics in biomedical research

生物医学研究中的统计主题

• 批准号: 3590-2007
• 负责人: Matthews, David
• 金额: $ 0.95万
• 依托单位: University of Waterloo
• 依托单位国家: 加拿大
• 项目类别: Discovery Grants Program - Individual
• 财政年份: 2007
• 资助国家: 加拿大
• 起止时间: 2007-01-01 至 2008-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=363670
• 关键词: Statistical; topics; biomedical; research

One of the goals of all statistical work is the estimation of key features of the measurement of interest in the target population.  An example of such a feature might be median household income, or perhaps the proportion of the adult population that suffers from diabetes.  These estimates can be expressed either as a specific value (a point estimate) or a range of plausible values (an interval estimate).  The spread of an interval estimate reflects the uncertainty with which the feature can be estimated using information obtained by sampling units from the target population, and measuring the feature on the units in the sample.The goal of the proposed research is to develop improved methods of deriving both point and interval estimates in various types of scientific studies, especially those carried out by researchers in medicine and public health.  Better methods of estimation should lead to more precise knowledge in all areas of research that depend on sampling and statistical analysis.

所有统计工作的目标之一是估计对目标人群的兴趣测量的关键特征。例如，这种特征可能是家庭收入中位数，或者可能是患有糖尿病的成年人口的比例。这些估计既可以表示为特定值(点估计)，也可以表示为一系列似是而非的值(区间估计)。区间估计的分布反映了使用抽样单位从目标人群获得的信息来估计特征的不确定性，并测量样本中单位的特征。拟议研究的目标是开发改进的方法，在各种类型的科学研究中得出点估计和区间估计，特别是由医学和公共卫生研究人员进行的研究。更好的估计方法应该导致依赖抽样和统计分析的所有研究领域的更准确的知识。