Research Fellowship
Research Fellowship
批准号:
nhmrc : 1019761
负责人:
Prof Richard Lewis
金额:
$49.34万
依托单位国家:
澳大利亚
项目类别:
Research Fellowships
财政年份:
2012
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2012-01-01 至 2016-12-31
关键词:
中文摘要
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英文摘要
Professor Lewis is a molecular pharmacologist interested in discovering new venom peptides and ciguatoxins and determining how they interact with the membrane proteins they target using advanced biochemical and spectroscopic methods. Peptides of interest are then modified to improve potency and selectivity. Those with appropriate properties are patented and developed for clinical applications using approaches successfully applied to Xen2174, a conopeptide analogue I co-discovered that is now in Phase II clinical trials for severe pain.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Conotoxin diversification and evolution of venom peptides in cone snails
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批准号:DP200103087
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项目类别:Discovery Projects
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资助金额:$37.88万
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财政年份:2020
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负责人:Prof Richard Lewis
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依托单位:
Evolution of defensive and predatory venom in cone snails
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批准号:DP170104792
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项目类别:Discovery Projects
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资助金额:$27.28万
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财政年份:2017
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负责人:Prof Richard Lewis
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依托单位:
Discovery and development of novel venom peptide analgesics
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批准号:nhmrc : GNT1119056
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项目类别:Research Fellowships
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资助金额:$76.38万
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财政年份:2017
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负责人:Prof Richard Lewis
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依托单位:
Discovery and development of novel venom peptide analgesics
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批准号:nhmrc : 1119056
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项目类别:Research Fellowships
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资助金额:$52.22万
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财政年份:2017
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负责人:Prof Richard Lewis
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依托单位:
Structure and function of predatory and defensive venoms in cone snails
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批准号:DP160103826
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项目类别:Discovery Projects
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资助金额:$32.91万
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财政年份:2016
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负责人:Prof Richard Lewis
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依托单位:
A VAST potential for ion channel drug discovery
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批准号:LP130101131
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项目类别:Linkage Projects
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资助金额:$41.17万
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财政年份:2013
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负责人:Prof Richard Lewis
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依托单位:
Probing norepinephrine transporter (NET) structure-function
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批准号:DP120101992
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项目类别:Discovery Projects
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资助金额:$19.32万
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财政年份:2012
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负责人:Prof Richard Lewis
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依托单位:
Role of extracellular surface residues in agonist activation of the alpha1 adrenoceptor
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批准号:nhmrc : 1004602
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项目类别:NHMRC Project Grants
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资助金额:$27.66万
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财政年份:2011
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负责人:Prof Richard Lewis
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依托单位:
Advanced molecular discovery and characterisation facility
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批准号:LE100100226
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项目类别:Linkage Infrastructure, Equipment and Facilities
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资助金额:$28.27万
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财政年份:2010
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负责人:Prof Richard Lewis
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依托单位:
Research Fellowship - Grant ID:455840
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批准号:nhmrc : 455840
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项目类别:NHMRC Research Fellowships
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资助金额:$41.26万
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财政年份:2007
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负责人:Prof Richard Lewis
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依托单位:
Biomolecular discovery and analysis facility
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批准号:LE0668526
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项目类别:Linkage Infrastructure, Equipment and Facilities
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资助金额:$36.14万
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财政年份:2006
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负责人:Prof Richard Lewis
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依托单位:
Probing central and peripheral calcium channel sybtypes with novel omega conotoxins
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批准号:nhmrc : 102585
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项目类别:NHMRC Project Grants
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资助金额:$25.55万
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财政年份:2000
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负责人:Prof Richard Lewis
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依托单位:
海外基金