Research Fellowship

研究奖学金

• 批准号: nhmrc : 1020983
• 负责人: Prof Graham Baldwin
• 金额: $ 50.06万
• 依托单位: The University of Melbourne
• 依托单位国家: 澳大利亚
• 项目类别: Research Fellowships
• 财政年份: 2012
• 资助国家: 澳大利亚
• 起止时间: 2012-01-01 至 2016-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/research-fellowship/110080
• 关键词: Research; Fellowship

My major goal for the past 20 years has been to understand how hormones such as gastrin stimulate the development of gastrointestinal cancer. One approach has been to define the intracellular signalling pathways by which gastrins enhance cell growth. Our discovery that iron is essential for the biological activity of gastrins may allow the development of novel therapies for colon cancer and iron overload.

在过去的20年里，我的主要目标是了解激素如胃泌素如何刺激胃肠道癌症的发展。一种方法是确定胃泌素促进细胞生长的细胞内信号通路。我们发现铁对于胃泌素的生物活性是必不可少的，这一发现可能有助于开发结肠癌和铁超载的新疗法。