Role of chromatid cohesion in colon biology and carcinogenesis
Role of chromatid cohesion in colon biology and carcinogenesis
染色单体凝聚力在结肠生物学和癌发生中的作用
批准号：
nhmrc : 1007659
负责人：
Dr Huiling Xu
金额：
$41.9万
依托单位国家：
澳大利亚
项目类别：
NHMRC Project Grants
财政年份：
2011
资助国家：
澳大利亚
项目状态：
已结题
起止时间：
2011-01-01 至 2013-12-31
中文摘要
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英文摘要
Rad21 is a gene, present in many species and essential for accurate chromosome separation and DNA damage repair. Based on its known function in different species, we predict that its� dysfunction fuels cancer progression by promoting genetic instability, which is commonly associated with human cancers. This study will use unique mouse mutant models to investigate the function of this potential cancer-causing gene in colon cancer.
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会议论文
Cohesin dysfunction: potential new route to tumourigenesis
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批准号：nhmrc : 400207
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项目类别：NHMRC Project Grants
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资助金额：$25.77万
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财政年份：2006
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负责人：Dr Huiling Xu
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依托单位：
Cohesin: role in germ cell chromosomal segregation
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批准号：nhmrc : 400310
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项目类别：NHMRC Project Grants
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资助金额：$29.04万
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财政年份：2006
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负责人：Dr Huiling Xu
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依托单位：
海外基金
