The role of ion channels in pain pathways

离子通道在疼痛通路中的作用

• 批准号: nhmrc : GNT1139961
• 负责人: Dr Jennifer Deuis
• 金额: $ 31.88万
• 依托单位国家: 澳大利亚
• 项目类别: Early Career Fellowships
• 财政年份: 2018
• 资助国家: 澳大利亚
• 起止时间: 2018-01-01 至 无数据
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/role-ion-channels-pain-pathways/1348273
• 关键词: role; ion; channels; pain; pathways

Pain is one of the most frequent and costly health problems faced by Australia. Currently available painkillers often do not work, or have intolerable side effects. We thus need better approaches to treat pain. This project will define the role of the novel pain target Nav1.6 in clinically relevant pain states, including burns pain and chemotherapy-induced pain, with the aim to develop novel treatment approaches and painkillers for these difficult-to-treat conditions.

疼痛是澳大利亚面临的最常见和最昂贵的健康问题之一。目前可用的止痛药往往不起作用，或有无法忍受的副作用。因此，我们需要更好的方法来治疗疼痛。该项目将定义新型疼痛靶标Nav1.6在临床相关疼痛状态中的作用，包括烧伤疼痛和化疗引起的疼痛，旨在为这些难以治疗的疾病开发新的治疗方法和止痛药。